| 09:00-09:45 |
PLENARY SESSION III: ETHICS |
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Jean Fleming (New Zealand)
Ethical, Cultural, and Spiritual Objections to Genetically Modified Organisms—A New Zealand Process and Perspective
Regency Ballroom E, F, G, H
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| 10:00-12:00 |
PARALLEL SESSION III |
A7: |
Organ Studies II: Neuro, Embryo, and Immuno Esplanade A
CHAIRS: Ellen Silbergeld (USA) and Sandra Coecke (Italy)
SPEAKERS:
Validation Strategies for Newly Developed Technologies in Neurotoxicology
Sandra Coecke (Italy)
An In Vitro System to Assess Neuronal Migration
Ellen Silbergeld (USA)
Improvement of the Embryonic Stem Cell Test by Establishing Molecular Endpoints of Tissue-Specific Development
Andrea Seiler (Germany)
A Humanized In Vitro High-Throughput Immunotechnology Platform
E.L. Roggen (Denmark)
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B6: |
Research on Animals for Animal Benefit Esplanade B
CHAIRS: David Morton (UK) and Mike Rickard (Australia)
SPEAKERS:
The Use of Animals for Research on Animal Diseases—Its Impact on the Harm-Benefit Analysis
Mike Rickard (Australia)
Vertebrate Pesticides and Traps: Are There Benefits for Animals?
Bruce Warburton (New Zealand)
The Ethics of Research on Companion Animals for the Benefit of Their Own Species
J.C. Conole (Australia)
Welfare Benefits to Farm Animals of Their Use in Research
I.G. Coldiz (Australia)
Scientific Program Incorporation of the Three R’s in Wildlife Research
Gilly Griffin (Canada)
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C5: |
Issues in Biotechnology Esplanade C
CHAIRS: Jean Fleming (New Zealand) and Tjard de Cock Buning (The Netherlands)
SPEAKERS:
Applying the Principles of Reduction and Refinement to the Generation, Management, and Care of Genetically Modified Mice—Sixth Report of the BVAAWF/FRAME/ RSPCA/UFAW Joint Working Group on Refinement
Maggy Jennings (UK)
Animal Use in Biotechnology: Issues and Options -- A New Zealand Regulatory Perspective
David Bayvel (New Zealand)
Effective Policies in the Animal Genomics Era: How to Best Involve Ethics, Expertise, and Public Participation
Lino Enrique Paula (The Netherlands)
Ethics, Transgenesis, and Cloning: Toward a Policy Framework Incorporating Welfare, Intrinsic Value, and Societal Perceptions
V. Monamy (Australia)
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D2: |
Transforming Undergraduate Education
with Alternatives Cabildo A
CHAIRS: Brigitte Rusche (Germany) and David Dewhurst (UK)
SPEAKERS:
Replacement of Harmful Animal Use in Life Science Education: The Approach and Activities of InterNICHE
Nick Jukes (UK)
Computer-based Alternatives to Using Animals in Teaching Physiology and Pharmacology to Undergraduate Students
David Dewhurst (UK)
Education, the Key for Improving Student Attitudes Toward the Use of Animal Alternatives in Research
Jan van der Valk (The Netherlands)
Our Experience with Developing Digitized Video Streams and Their Use in Animal-Free Teaching in Medical Education
Miroslav Cervinka (Czech Republic)
The Psychological Effects on Students of Using Animals in Ways that They See as Ethically, Morally, or Religiously Wrong
Theodora Capaldo (USA)
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E6: |
Eye Toxicity Cabildo B
CHAIRS: Odile de Silva (France) and Dan Bagley (USA)
SPEAKERS:
The Research Program of the Steering Committee on Alternatives to Animal Testing (SCAAT) Poydras A/B
Odile de Silva (France)
A Reproducible Tissue Model for Ocular Irritancy Testing
John Sheasgreen (USA) and Mitch Klausner (USA)
Three-dimensional Construct of the Human Corneal Epithelium for In Vitro Toxicology
D.H. Nguyen (USA)
Evaluation of a New In Vitro Human Cornea Model as an Alternative to the In Vivo Rabbit Eye Draize Test
F. van Goethem (Belgium)
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W-A5: |
Statistical Reduction Strategies and Using In Vitro Data as Part of a Reduction Strategy Cabildo C
MODERATORS: Michael Festing (UK) and Raj Chhabra (USA)
SPEAKERS:
Good Experimental Design and Statistics Can Save Animals, but How can it be Promoted?
Michael Festing (UK)
Evaluation of Some In Vitro Tests to Reduce and Replace the Sub-acute Animal Toxicity Tests
Raj Chhabra (USA)
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W-A3: |
Genomics, Proteomics, and Metabonomics Poydras A/B
Moderators: André Schrattenholz (Germany) and Brian Jones (USA)
Genomics, Proteomics, and Metabonomics
Brian Jones (USA)
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| 13:00-14:00 |
WORKSHOPS/POINT-COUNTERPOINT SESSION II |
W-A4: |
Cryobiology/Low-temperature Preservation of Cells and Tissues Esplanade A
Moderators: Locksley McGann (Canada) and John Critser (USA) |
W-A2: |
Replacement in Monoclonal Antibody Production Esplanade B
Moderators: Coenraad Hendriksen (The Netherlands), John McArdle (USA), and Simon Saxby (UK) |
W-C2: |
Euthanasia Guidelines and Practices Esplanade C
Moderators: Vera Baumans (Sweden) and Larry Carbone (USA)
SPEAKERS:
Euthanasia of Laboratory Animals: What is Best for Animal and Experiment?
Vera Baumans (Sweden)
Establishing Science-based Animal Care and Euthanasia Policy When the Data Are Incomplete
Larry Carbone (USA)
Laboratory Rodent Aversion to Agents of Anesthesia and Euthanasia
David Morton (UK) |
PCP-C2: |
A Different View of Animal Research Poydras A/B
Moderator: Michael Balls (UK)
Speaker:
Bruegel's Two Monkeys, or, Why Finding Alternatives to Animal Tests Matters
Ingrid Newkirk (USA) |
W-D2: |
Resources for Teachers Cabildo B
Moderators: Jasmijn de Boo (The Netherlands) and Lesley King (USA)
SPEAKERS:
Information Databases on Alternatives to Animals in Education and Training: NORINA and TextBase
Adrian Smith (Norway)
The European Resource Centre for Alternatives in HE
Jan van der Valk (The Netherlands), Jasmijn de Boo (The Netherlands), and David Dewhurst (UK)
InterNICHE and Other Resources
Nick Jukes (UK) |
W-D5: |
Changes in Technician Training: Developing New Attitudes Cabildo C
Moderators: Sally Walshaw (USA) and Harry Blom (The Netherlands)
SPEAKERS:
Teaching from the Heart: Teaching to Care and to Respect
Sallly Walshaw (USA)
Teaching Laboratory Animal Science to Scientists -- Aiming for Attitude or Skills?
Harry Blom (The Netherlands)
Use of Animals in College and Veterinary Education at the University of California, Davis: Institutional Commitment for Mainstreaming Alternatives
Lynette Hart (USA) |
W-E4: |
Report from the ICLAS-CCAC International Symposium on Regulatory Testing and Animal Welfare Cabildo A
Moderators: Clement Gauthier (Canada), S. Pakes (USA), Gilly Griffin (Canada), and William Stokes (USA) |
| 14:15-16:15 |
PARALLEL SESSION IV |
A3: |
In Vitro Reconstituted Human Tissue Models Esplanade A
CHAIRS: John Harbell (USA) and Roland Roguet (France)
SPEAKERS:
Application of Human Tissue Constructs to In Vitro Toxicology
John Harbell (USA)
Scientific Program
The Use of Reconstructed Human Epidermis EPISKINTM in the Assessment of Efficacy and Local Tolerance of Cosmetics and Chemicals
Roland Roguet (France)
Full Thickness EpidermTM: a Dermal-Epidermal Skin Model to Study Epithelial-Mesenchymal Interactions
Mitch Klausner (USA) and John Sheasgreen (USA)
cDNA Array-based Analysis of Gene Expression Profile in Three Different Models of Reconstructed Human Epidermis
François Bernerd (France)
Advanced Skin Test 2000 (AST-2000): Reconstructed Human Skin Designed for Dermatological and Pharmaceutical Research
Jens J. Hoffman (Germany)
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B7: |
Experimental Design: A Tool to Promote Refinement and Reduction Esplanade B
CHAIRS: Derek Fry (UK) and H. van Wilgenburg (The Netherlands)
SPEAKERS:
Reduction by Well-Defined Objectives
Derek Fry (UK)
Optimizing Resources by Reduction: The Work of the FRAME Reduction Committee
Sylvia Vaughan (UK)
Computer Simulation for Improving the Precision of an Experiment
H. van Wilgenburg (The Netherlands)
Reduction by Use of Factorial Experimental Design
R. Shaw (UK)
Adequate Statistical Methods to Reduce the Number of Animals Used in Behavioral Experiments: The Analysis of the Behavioral Sequences
M. Puopolo (Italy) |
C4: |
Putting Policy into Practice: Ethical Analysis and National Standards Esplanade C
CHAIRS: David Bayvel (New Zealand) and Jon Richmond (UK)
SPEAKERS:
Humane Regulatory Testing: The United Kingdom Experience
Jon Richmond (UK)
TestSmartTM and Toxic Ignorance
Sidney Green (USA)
Scientific Program The Initiative of ECOPA: The Way Forward
Vera Rogiers (Belgium)
EU Sales Ban on New Cosmetics Tested on Animals: Impact on Alternative Methods, WTO Implications, and Animal Welfare Aspects
Irma Ruhdel (Germany), presented by Ursula Sauer (Germany) |
D4: |
New Technologies in Developing Animal Alternaties Cabildo A
CHAIRS: Jonathan Balcombe (USA) and Alex Davies (New Zealand)
SPEAKERS:
Medical Training Using Virtual Reality: Fewer Animals, Safer Patients
Jonathan Balcombe (USA)
Technological Advances that Enhance Teaching Using Animals, and the Application of the Three R’s
Alexander S. Davies (New Zealand)
How Can We Encourage Teachers to Use Computerbased Alternatives: The UK HE Experience
David Dewhurst (UK)
Virtual Physiology Labs: Concepts and Teaching Experiences
Hans Braun (Germany) |
E4: |
Acute Systemic Toxicity Testing: Validation and Implementation of Alternative Methods Cabildo B
CHAIRS: Phil Botham (UK) and Kathy Stitzel (USA)
SPEAKERS:
Acute Systemic Toxicity Testing: Overview of Recent Key Activities
Phil Botham (UK)
Evaluation of Cytotoxicity Models for Predicting Acute Oral Toxicity Test Starting Doses
Rodger Curren (USA)
Is It Really Possible to Bear Test Guideline 401 to Burial?
Herman Koëter (France)
The Use of In Vitro Data to Estimate Starting Doses for Acute Oral In Vivo Studies
Manfred Liebsch (Germany)
Comparison and Validation of Novel Pyrogen Tests Based on the Human Fever Reaction
Thomas Hartung (Germany) |
W-B2: |
Refinement in Generation and Maintenance of Transgenics: Local Anesthesia, Cryopreservation, and Clinical Assessment of Phenotype Cabildo C
Moderators: Tory Hampshire (USA) and David Morton (UK)
SPEAKERS:
Refinement in Transgenic Management
David Morton (UK)
Genotyping Mice with Care: Buccal Cell Collection on Mice Results in a Gentler, Cheaper, More
Simplified Protocol
M. Boyd (Canada)
The Management of Animal Welfare by Clinical Observations and an Integrated Information System
J.M. Fentener (The Netherlands) |
| 16:45-17:30 |
PLENARY SESSION IV: EDUCATION Regency Ballroom E, F, G, H |
|
Adrian Smith (Norway)
What Educational Research has to Say About the Usefulness of Animals and Alternatives in Teaching Biology, Medicine, and the Associated Technical Skills |