Ian Kimber (UK)
The Search for Alternatives for Hypersensitivity Testing: Lessons for the Development and Validation of Alternative Tests
Regency Ballroom E, F, G, H

A8:

Skin Sensitization Esplanade A
CHAIRS: Ian Kimber (UK) and Frank Gerberick (USA)

SPEAKERS:
Understanding the Chemical Basis of Contact Allergy in the Development of Alternative Methods
Frank Gerberick (USA)

A Genomics Approach for the Development of an In Vitro Method for Skin Sensitization
C. A. Ryan (USA)

B3:

New Developments in Monitoring Animal Physiology and Behavior Esplanade B
CHAIRS: Bernward Garthoff (Germany) and Rosemarie Einstein (Australia)

SPEAKERS:
Implanted Telemetry Transmitters Alter the Noradrenergic Response in Vas Deferens from Mice
Rosemarie Einstein (Australia)

Does Conditioning Influence the Increase of Heart Rate and Body Temperature as Provoked by Handling in the Mouse?
Klaas Kramer (The Netherlands)

Evaluation of a Behavior-based Post-operative Pain Scoring System in Rats
Paul Flecknell (UK)

Scientific Program Refinement of the Lethal Endpoint for Testing of Leptospiral Vaccines in the Hamster Model: Infrared Body Temperature Measurement and Other Strategies
Paul Townsend (UK)

A CD-ROM on the Whole Cell Pertussis Vaccine Potency Test for Reducing Test Variability and for Implementing Humane Endpoints
Coenraad Hendricksen (The Netherlands)

C7:

Ethical Analysis and National Standards Esplanade C
CHAIRS: Neil Wells (New Zealand) and Nelson Garnett (USA)

SPEAKERS:
Five Plus Three: Legislating for the Five Freedoms and the Three R’s—Animal Welfare Act 1999 (New Zealand)
Neil Wells (New Zealand)

The Humane Society of the United States’ Pain and Distress Initiative
Martin L. Stephens (USA)

Ethical Review Committees in The Netherlands: Looking Back and Forward
Wim de Leeuw (The Netherlands)

Ethical Evaluation of Research Proposals by Ethics Panels Advising the European Commission
Roman Kolar (Germany)

Achievements in Raising Awareness on the Use of Alternative Methods in Latin America and the Caribbean
Gisela Murillo (Cuba)

A5:

Incorporation of In Vitro-Derived Data on Biokinetics and Toxicodynamics in Risk Assessments Cabildo A
CHAIRS: Bas Blaauboer (The Netherlands) and Harvey Clewell (USA)

SPEAKERS:
The Use of Biokinetic Modeling and In Vitro Data to Reduce the Requirement for In Vivo Animal Testing
Harvey Clewell (USA)

Use of a Perfusion Co-culture System Consisting of Caco-2 and Hep G2 Cell Compartments for the Kinetic Analysis of Benzo[a]pyrene Toxicity
Y. Sakai (Japan)

Prediction of Whole Body Metabolic Clearance of Drugs through the Combined Use of Slices from Rat Liver, Lung, Kidney, Small Intestine, and Colon
G.M.M. Groothuis (The Netherlands)

Scientific Program Integration of In Vitro-Derived Toxicity Data and Biokinetics in Strategies for Hazard and Risk Assessment of Chemicals
Bas Blaauboer (The Netherlands)

Monitoring of Muscle and Connective Tissue Metabolite Concentrations Intramuscularly and Subcutaneously in the Isolated Hemoperfused Porcine Forelimb Microdialysis
B. Christ (Germany)

E5:

Neurotoxicity and Developmental Toxicity: Development, Validation, and Implementation of Alternatives and New Methods Cabildo B
CHAIRS: Sidney Green (USA) and Hiroshi Ono (Japan)

SPEAKERS:
The ECVAM International Validation Study on Three In Vitro Embryotoxicity Tests
Horst Spielmann (Germany)

Developmental Neurotoxicity Test Guidelines
Susan Makris (USA)

Genetically Altered Mouse Models: Short-term Alternatives to Two-year Carcinogenicity Testing
John French (USA)

Cell Transformation Assay Using Balb/c 3T3 Cells or Bhas 42 Cells for the Efficient Detection of Tumor Promoters
Makoto Umeda (Japan)

The Alkaline Comet Assay: A Proposed Alternative Test Method for the Detection of Genotoxic Carcinogens
Raymond Tice (USA)

E8:

Organ-specific Models III Cabildo C
CHAIRS: Eugene Elmore (USA) and June Bradlaw (USA)

SPEAKERS:
Using Normal Human Epithelial Cells to Predict Chemopreventive Agent Efficacy and Toxicity: Correlations with Clinical Trial Plasma Levels, Biomarkers, and Adverse Effects
Eugene Elmore (USA)

An Innervated Tissue-Engineered Human Cornea for In Vitro Testing
May Griffith (Canada)

Scientific Program Validation of an Exposure Technique for Testing the Biological Activity of Gases and Complex Atmospheres In Vitro
M. Aufderheide (Germany)

EpiVaginal, A Human Tissue Model for Vaginal Irritation Studies
M. Klausner (USA)

In Vitro Safety Evaluation of Anti-fungal Agents
E. Herreros (Spain)