CONTENTS

CHAIRS' WELCOME

FINANCIAL SUPPORT

EXHIBITORS

CONGRESS ORGANIZATION

MAP

PROGRAM OUTLINE

SCIENTIFIC PROGRAM

PLENARY LECTURES

PRESENTER ABSTRACTS

Theme A: Replacement and Reduction Alternatives

Session A1: The Acquisition and Use of Human Cells in Research and Testing
Chairs: Robert Combes (UK) and Jan van der Valk (The Netherlands)

Session A2: Immortalization Versus Redifferentiation of Cell Lines
Chairs: Jose Castell (Spain) and William Smith (USA)

Session A3: In Vitro Reconstituted Human Tissue Models
Chairs: John Harbell (USA) and Roland Roguet (France)

Session A4: Vaccines and Biologicals: Application of the Three R's
Chairs: Coenraad Hendriksen (The Netherlands) and Klaus Cussler (Germany)

Session A5: Incorporation of In Vitro-Derived Data on Biokinetics and Toxicodynamics in Risk Assessments
Chairs: Bas Blaauboer (The Netherlands) and Harvey Clewell (USA)

Session A6: Organ Studies I (Liver and Drug Metabolism)
Chairs: Vera Rogiers (Belgium) and Jose Castell (Spain)

Session A7: Organ Studies II (Neuro, Embryo, and Immuno)
Chairs: Ellen Silbergeld (USA) and Sandra Coecke (Italy)

Session A8: Skin Sensitization
Chairs: Ian Kimber (UK) and Frank Gerberick (USA)

Workshop/Point-Counterpoint Abstracts

Theme B: Refinement and Reduction Alternatives

Session B1: Enrichment, Science, and Animal Welfare
Chairs: Kathryn Bayne (USA) and Joe Garner (USA)

Session B2: Evaluation Techniques for Animal Well-Being
Chairs: Vera Baumans (Sweden) and David Mellor (New Zealand)

Session B3: New Developments in Monitoring Animal Physiology and Behavior
Chairs: Bernward Garthoff (Germany) and Rosemarie Einstein (Australia)

Session B4: Animal Welfare: Guidelines and Beyond
Chairs: Jean-Marc Spieser (France) and David Anderson (UK)

Session B5: Novel Methods for Science--Welfare Concerns
Chairs: Christian Cook (New Zealand) and James Kirkwood (UK)

Session B6: Research on Animals for Animal Benefit
Chairs: David Morton (UK) and Mike Rickard (Australia)

Session B7: Experimental Design: A Tool to Promote Refinement and Reduction
Chairs: Derek Fry (UK) and H. van Wilgenburg (The Netherlands)

Workshop/Point-Counterpoint Abstracts

Theme C: Policy and Ethics

Session C1: Animal Numbers and Trends from Around the World
Chairs: Paul de Greeve (The Netherlands) and Clément Gauthier (Canada)

Session C2: Ethical Issues in Primate Research
Chairs: Ursula G. Sauer (Germany) and Kathryn Bayne (USA)

Session C3: Policy Aspects of Chemicals Testing Initiatives and Alternatives
Chairs: Philip Sayre (USA) and Michael Balls (UK)

Session C4: Putting Policy into Practice: Ethical Analysis and National Standards
Chairs: David Bayvel (New Zealand) and Jon Richmond (UK)

Session C5: Issues in Biotechnology
Chairs: Jean Fleming (New Zealand) and Tjard de Cock Buning (The Netherlands)

Session C6: Issues in Animal Research
Chairs: Derek Fry (UK) and Ken Shapiro (USA)

Session C7: Ethical Analysis and National Standards
Chairs: Neil Wells (New Zealand) and Nelson Garnett (USA)

Workshop/Point-Counterpoint Abstracts

Theme D: Education and Information Resources

Session D1: Transforming Middle and High School Education with Animal Alternatives
Chairs: Lynette Hart (USA) and Steve Zawistowski (USA)

Session D2: Transforming Undergraduate Education with Alternatives
Chairs: Brigitte Rusche (Germany) and David Dewhurst (UK)

Session D3: Three R's Education for Those Involved in Animal-based Research
Chairs: Nicole Duffee (USA) and Bert van Zutphen (The Netherlands)

Session D4: New Technologies in Developing Animal Alternatives
Chairs: Jonathan Balcombe (USA) and Alex Davies (New Zealand)

Session D5: Information Providers, Resources, Tools, and Databases
Chairs: Barbara Grune (Germany) and Lisa Libowitz (USA)

Workshop/Point-Counterpoint Abstracts

Special Satellite Session--Sunday

Theme E: Test Development, Validation, and Implementation

Session E1: Validation of Alternative Test Methods: Recent Progress and New Initiatives
Chairs: William Stokes (USA) and Julia Fentem (UK)

Session E2: Regulatory Acceptance of Alternative Methods: Recent Progress and New Initiatives
Chairs: Len Leonard Schechtman (USA) and Julia Fentem (UK)

Session E3: Validation and Implementation of Alternative Methods for Identifying Endocrine Disrupters and Reproductive Toxicants
Chairs: Gary Timm (USA) and Tohru Inoue (Japan)

Session E4: Acute Systemic Toxicity Testing: Validation and Implementation of Alternative Methods
Chairs: Philip Botham (UK) and Kathy Stitzel (USA)

Session E5: Neurotoxicity and Developmental Toxicity: Development, Validation, and Implementation of Alternatives and New Methods
Chairs: Sidney Green (USA) and Hiroshi Ono (Japan)

Session E6: Eye Toxicity
Chairs: Odile de Silva (France) and Dan Bagley (USA)

Session E7: Skin and Phototoxicity
Chairs: Manfred Liebsch (Germany) and Roland Roguet (France)

Session E8: Organ-Specific Models III Chairs: Eugene Elmore (USA) and June Bradlaw (USA)

Workshop/Point-Counterpoint Abstracts

POSTER ABSTRACTS

Theme A: Replacement And Reduction Alternatives

Theme B Posters: Refinement and Reduction Alternatives

Theme C Posters: Policy and Ethics

Theme D Posters: Education and Information Resources

Theme E Posters: Test Development, Validation, And Implementation

AUTHOR INDEX

POSTER INDEX